Publications

2015

MxB Is Not Responsible for the Blocking of HIV-1 Infection Observed in Alpha Interferon-Treated Cells.

Opp S, Vieira DA, Schulte B, Chanda SK, Diaz-Griffero F.

J Virol. 2015 Dec 30;90(6):3056-64. doi: 10.1128/JVI.03146-15.

PMID: 26719253 Free PMC article.

Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.

Tripathi S, Pohl MO, Zhou Y, Rodriguez-Frandsen A, Wang G, Stein DA, Moulton HM, DeJesus P, Che J, Mulder LC, Yángüez E, Andenmatten D, Pache L, Manicassamy B, Albrecht RA, Gonzalez MG, Nguyen Q, Brass A, Elledge S, White M, Shapira S, Hacohen N, Karlas A, Meyer TF, Shales M, Gatorano A, Johnson JR, Jang G, Johnson T, Verschueren E, Sanders D, Krogan N, Shaw M, König R, Stertz S, García-Sastre A, Chanda SK.

Cell Host Microbe. 2015 Dec 9;18(6):723-35. doi: 10.1016/j.chom.2015.11.002.

PMID: 26651948 Free PMC article.

Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy.

Lau E, Sedy J, Sander C, Shaw MA, Feng Y, Scortegagna M, Claps G, Robinson S, Cheng P, Srivas R, Soonthornvacharin S, Ideker T, Bosenberg M, Gonzalez R, Robinson W, Chanda SK, Ware C, Dummer R, Hoon D, Kirkwood JM, Ronai ZA.

Oncogene. 2015 Nov 12;34(46):5739-48. doi: 10.1038/onc.2015.22. Epub 2015 Mar 2.

PMID: 25728676 Free PMC article.

BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.

Pache L, Dutra MS, Spivak AM, Marlett JM, Murry JP, Hwang Y, Maestre AM, Manganaro L, Vamos M, Teriete P, Martins LJ, König R, Simon V, Bosque A, Fernandez-Sesma A, Cosford ND, Bushman FD, Young JA, Planelles V, Chanda SK.

Cell Host Microbe. 2015 Sep 9;18(3):345-53. doi: 10.1016/j.chom.2015.08.009.

PMID: 26355217 Free PMC article.

HIV-1 protease cleaves the serine-threonine kinases RIPK1 and RIPK2

Wagner RN, Reed JC, Chanda SK.

Retrovirology. 2015 Aug 22;12:74. doi: 10.1186/s12977-015-0200-6.

PMID: 26297639 Free PMC article.

PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.

Yoh SM, Schneider M, Seifried J, Soonthornvacharin S, Akleh RE, Olivieri KC, De Jesus PD, Ruan C, de Castro E, Ruiz PA, Germanaud D, des Portes V, García-Sastre A, König R, Chanda SK.

Cell. 2015 Jun 4;161(6):1293-1305. doi: 10.1016/j.cell.2015.04.050.

PMID: 26046437 Free PMC article.

A Potent Anti-influenza Compound Blocks Fusion through Stabilization of the Prefusion Conformation of the Hemagglutinin Protein.

White KM, De Jesus P, Chen Z, Abreu P Jr, Barile E, Mak PA, Anderson P, Nguyen QT, Inoue A, Stertz S, Koenig R, Pellecchia M, Palese P, Kuhen K, García-Sastre A, Chanda SK, Shaw ML.

ACS Infect Dis. 2015 Feb 13;1(2):98-109. doi: 10.1021/id500022h. Epub 2014 Dec 15.

PMID: 25984567 Free PMC article.

2014

RIOK3 is an adaptor protein required for IRF3-mediated antiviral type I interferon production.

Feng J, De Jesus PD, Su V, Han S, Gong D, Wu NC, Tian Y, Li X, Wu TT, Chanda SK, Sun R.

J Virol. 2014 Jul;88(14):7987-97. doi: 10.1128/JVI.00643-14. Epub 2014 May 7.

PMID: 24807708 Free PMC article.

Tumor suppressor cylindromatosis (CYLD) controls HIV transcription in an NF-κB-dependent manner.

Manganaro L, Pache L, Herrmann T, Marlett J, Hwang Y, Murry J, Miorin L, Ting AT, König R, García-Sastre A, Bushman FD, Chanda SK, Young JA, Fernandez-Sesma A, Simon V.

J Virol. 2014 Jul;88(13):7528-40. doi: 10.1128/JVI.00239-14. Epub 2014 Apr 23.

PMID: 24760882 Free PMC article.

An integrated map of HIV-human protein complexes that facilitate viral infection.

Emig-Agius D, Olivieri K, Pache L, Shih HL, Pustovalova O, Bessarabova M, Young JA, Chanda SK, Ideker T.

PLoS One. 2014 May 9;9(5):e96687. doi: 10.1371/journal.pone.0096687. eCollection 2014.

PMID: 24817247 Free PMC article.

Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-γ.

Opaluch AM, Schneider M, Chiang CY, Nguyen QT, Maestre AM, Mulder LC, Secundino I, De Jesus PD, König R, Simon V, Nizet V, MacLeod G, Varmuza S, Fernandez-Sesma A, Chanda SK.

PLoS One. 2014 Feb 20;9(2):e89284. doi: 10.1371/journal.pone.0089284. eCollection 2014.

PMID: 24586659 Free PMC article.

2013

A short hairpin RNA screen of interferon-stimulated genes identifies a novel negative regulator of the cellular antiviral response.

Li J, Ding SC, Cho H, Chung BC, Gale M Jr, Chanda SK, Diamond MS.

mBio. 2013 Jun 18;4(3):e00385-13. doi: 10.1128/mBio.00385-13.

PMID: 23781071 Free PMC article.

2012

Identification of small molecules that interfere with H1N1 influenza A viral replication.

Bottini A, De SK, Baaten BJ, Wu B, Barile E, Soonthornvacharin S, Stebbins JL, Bradley LM, Chanda SK, Pellecchia M.

ChemMedChem. 2012 Dec;7(12):2227-35. doi: 10.1002/cmdc.201200453. Epub 2012 Nov 8.

PMID: 23139022 Free PMC article.

Functional genomic and high-content screening for target discovery and deconvolution.

Heynen-Genel S, Pache L, Chanda SK, Rosen J.

Expert Opin Drug Discov. 2012 Oct;7(10):955-68. doi: 10.1517/17460441.2012.711311. Epub 2012 Aug 4.

PMID: 22860749 Free PMC article. Review.

Cofactors required for TLR7- and TLR9-dependent innate immune responses.

Chiang CY, Engel A, Opaluch AM, Ramos I, Maestre AM, Secundino I, De Jesus PD, Nguyen QT, Welch G, Bonamy GM, Miraglia LJ, Orth AP, Nizet V, Fernandez-Sesma A, Zhou Y, Barton GM, Chanda SK.

Cell Host Microbe. 2012 Mar 15;11(3):306-18. doi: 10.1016/j.chom.2012.02.002.

PMID: 22423970 Free PMC article.

Fer kinase regulates cell migration through α-dystroglycan glycosylation.

Yoneyama T, Angata K, Bao X, Courtneidge S, Chanda SK, Fukuda M.

Mol Biol Cell. 2012 Mar;23(5):771-80. doi: 10.1091/mbc.E11-06-0517. Epub 2012 Jan 11.

PMID: 22238358 Free PMC article.